Impact of Bariatric Surgery on Moderate to Severe Psoriasis: A Retrospective Nationwide Registry Study

Studies of the effects of bariatric surgery on psoriasis are few, with conflicting results. By linking the Swedish National Register for Systemic Treatment of Psoriasis (PsoReg) with the Scandinavian Obesity Surgery Registry (SOReg), individuals with psoriasis who had undergone bariatric surgery in...

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Main Authors: Marta Laskowski (Author), Linus Schiöler (Author), Johan Ottosson (Author), Marcus Schmitt-Egenolf (Author), Ann-Marie Wennberg (Author), Torsten Olbers (Author), Kjell Torén (Author), Helena Gustafsson (Author)
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Published: Medical Journals Sweden, 2021-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Marta Laskowski  |e author 
700 1 0 |a Linus Schiöler  |e author 
700 1 0 |a Johan Ottosson  |e author 
700 1 0 |a Marcus Schmitt-Egenolf  |e author 
700 1 0 |a Ann-Marie Wennberg  |e author 
700 1 0 |a Torsten Olbers  |e author 
700 1 0 |a Kjell Torén  |e author 
700 1 0 |a Helena Gustafsson  |e author 
245 0 0 |a Impact of Bariatric Surgery on Moderate to Severe Psoriasis: A Retrospective Nationwide Registry Study 
260 |b Medical Journals Sweden,   |c 2021-06-01T00:00:00Z. 
500 |a 0001-5555 
500 |a 1651-2057 
500 |a 10.2340/00015555-3825 
520 |a Studies of the effects of bariatric surgery on psoriasis are few, with conflicting results. By linking the Swedish National Register for Systemic Treatment of Psoriasis (PsoReg) with the Scandinavian Obesity Surgery Registry (SOReg), individuals with psoriasis who had undergone bariatric surgery in Sweden during 2008 to 2018 were identified, and matched with data for patients with psoriasis in PsoReg. Psoriasis Area Severity Index (PASI) and Dermatology Life Quality Index (DLQI) were compared between the groups. Altogether, 50 operated individuals (median body mass index (BMI) 38.7 kg/m2]) and 91 non-operated individuals (median BMI 33.0 kg/m2) were included. Control of disease at baseline was good in both groups. Linear mixed models showed no significant difference in psoriasis disease burden, measured as changes in mean PASI (ΔPASI) (-1.2, p = 0.43) and DLQI (ΔDLQI) (-2.2, p = 0.34). In summary, this study demonstrated no significant effect of bariatric surgery on psoriasis disease burden in patients with relatively well-controlled moderate to severe psoriasis. 
546 |a EN 
690 |a psoriasis 
690 |a  bariatric surgery 
690 |a  body mass index 
690 |a  swedish national register for systemic treatment of psoriasis 
690 |a  scandinavian obesity surgery registry 
690 |a  psoriasis area severity index 
690 |a  dermatology life quality index 
690 |a  obesity 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Acta Dermato-Venereologica, Vol 101, Iss 6, p adv00487 (2021) 
787 0 |n  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3825  
787 0 |n https://doaj.org/toc/0001-5555 
787 0 |n https://doaj.org/toc/1651-2057 
856 4 1 |u https://doaj.org/article/49b4b1d097744cecac1fc3aa1d33e40d  |z Connect to this object online.