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THE SIGNIFICANCE OF QUANTITIES DETECTION OF СORE ANTIGEN IN BLOOD SERUM OF CHILDREN WITH HEPATITIS C

The clinical and pathogenetic significance of determining HCV core-antigen (HCV core-Ag) in serum of children with hepatitis C was investigated firstly. A direct correlation between the concentration of HCV core-Ag and viral load (VL) was revealed (r = 0,91). Children with high core-Ag (above 2500 f...

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Main Authors: A. Leybman (Author), L. I. Nikolaeva (Author), G. V. Sapronov (Author), E. I. Shestakova (Author), E. I. Samokhvalov (Author), O. B. Kovalev (Author), A. G. Pisarev (Author), L. I. Konovalova (Author), A. E. Grishechkin (Author), V. F. Uchaikin (Author)
Format: Book
Published: LLC "Diagnostics and Vaccines", 2015-08-01T00:00:00Z.
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Summary:The clinical and pathogenetic significance of determining HCV core-antigen (HCV core-Ag) in serum of children with hepatitis C was investigated firstly. A direct correlation between the concentration of HCV core-Ag and viral load (VL) was revealed (r = 0,91). Children with high core-Ag (above 2500 fmol/L) showed indirect evidence for the immunosuppressive action of HCV core-Ag and occurrence of liver fibrosis more frequent (p < 0,05). In this grouP of children the prevalence of HCV subtype 3a was revealed (p < 0,05).
Item Description:2072-8107
10.22627/2072-8107-2014-13-2-8-12

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