Role of Zinc Supplementation in the Treatment of Levetiracetam-Induced Hair Loss: A Case Series

Objective: Cosmetic side effects are of important causes for non-compliance in patients on anti-epileptics. TE is among the most encountered cosmetic adverse effects. Method: This report presents three patients with seizure disorder who developed levetiracetam- induced TE. Levetiracetam was consider...

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Bibliographic Details
Main Authors: Vajiheh Aghamollaii (Author), Zahra Ghelich Khan (Author), Andisheh Maneshi (Author), Padideh Ghaeli (Author)
Format: Book
Published: Research Center for Rational Use of Drugs (RCRUD), 2017-09-01T00:00:00Z.
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Summary:Objective: Cosmetic side effects are of important causes for non-compliance in patients on anti-epileptics. TE is among the most encountered cosmetic adverse effects. Method: This report presents three patients with seizure disorder who developed levetiracetam- induced TE. Levetiracetam was considered the best therapeutic option for the treatment of the presented patients and therefore, was not changed to other anti-epileptics. To manage TE, it was decided to add Zinc sulfate to the therapeutic levetiracetam regimen. Results:  All three patients reported improvement in their hair condition while their seizure was controlled. Significance: Levetiracetam has favorable safety and efficacy profiles. However; the hair loss caused by this medication is a major drawback. Zinc supplementation is suggested to be safe and cost effective when considering management of levetiracetam-induced TE.
Item Description:2322-4630
2322-4509