Biosynthesis and Heterologous Expression of Cacaoidin, the First Member of the Lanthidin Family of RiPPs

• Main Authors: Fernando Román-Hurtado (Author), Marina Sánchez-Hidalgo (Author), Jesús Martín (Author), Francisco Javier Ortiz-López (Author), Olga Genilloud (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cacaoidin is produced by the strain <i>Streptomyces cacaoi</i> CA-170360 and represents the first member of the new lanthidin (class V lanthipeptides) RiPP family. In this work, we describe the complete identification, cloning and heterologous expression of the cacaoidin biosynthetic gen...