THE ROLE OF MELATONIN DEFICIENCY IN THE GENESIS OF ARTERIAL HYPERTENSION IN PATIENTS WITH CHRONIC KIDNEY DISEASE
The study analyzed the prevalence of hypertension and impaired melatonin-forming function of the epiphysis in patients with stage 5 chronic kidney disease treated with hemodialysis. The relationship between epiphysis dysfunction and hypertension has been identified. 130 persons (50% of men) undergoi...
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| Main Authors: | , |
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| Format: | Book |
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Bogomolets National Medical University,
2020-07-01T00:00:00Z.
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| Summary: | The study analyzed the prevalence of hypertension and impaired melatonin-forming function of the epiphysis in patients with stage 5 chronic kidney disease treated with hemodialysis. The relationship between epiphysis dysfunction and hypertension has been identified. 130 persons (50% of men) undergoing permanent hemodialysis treatment were examined. Controls were 20 healthy individuals. The determination of daytime and nighttime levels of melatonin in saliva and clinical and laboratory studies. As a result of the study it was found that for patients with stage 5 chronic kidney disease undergoing treatment, there is a frequent violation of melatonin-forming function of the pineal gland (84.6%) and hypertension (78%). In hemodialysis patients, blood pressure increases are age-dependent and are determined with salivary melatonin levels. |
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| Item Description: | 2786-6661 2786-667X 10.32345/USMYJ.1(115).2020.18-26 |