Identification of novel CYP2D7-2D6 hybrids: non-functional and functional variants
Polymorphic expression of CYP2D6 contributes to the wide range of activity observed for this clinically important drug metabolizing enzyme. In this report we describe novel CYP2D7/2D6 hybrid genes encoding non-functional and functional CYP2D6 protein and a CYP2D7 variant that mimics a CYP2D7/2D6 hyb...
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Main Authors: | Andrea Gaedigk (Author), Lazara K M Jaime (Author), Joseph S Bertino, Jr (Author), Anick Bérard (Author), Victoria Pratt (Author), L D Bradford (Author), J S Leeder (Author) |
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Format: | Book |
Published: |
Frontiers Media S.A.,
2010-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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