Synthesis of novel 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines and their antihyperglycemic activity

A number of 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines 6a-f derivatives were synthesized and their antihyperglycemic activity was evaluated by streptozotocin (STZ) and sucrose-loaded model. Many of oxazolidine derivatives as well as their corresponding substituted phenyl...

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Kaituhi matua: T Panneerselvam (Author)
Hōputu: Pukapuka
I whakaputaina: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
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245 0 0 |a Synthesis of novel 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines and their antihyperglycemic activity 
260 |b Wolters Kluwer Medknow Publications,   |c 2011-01-01T00:00:00Z. 
500 |a 2231-4040 
500 |a 0976-2094 
500 |a 10.4103/2231-4040.79804 
520 |a A number of 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines 6a-f derivatives were synthesized and their antihyperglycemic activity was evaluated by streptozotocin (STZ) and sucrose-loaded model. Many of oxazolidine derivatives as well as their corresponding substituted phenylhydrazine showed significant reduction in blood glucose level in STZ and sucrose-loaded rat models. 
546 |a EN 
690 |a Antihyperglycemic activity 
690 |a oxazolidine 
690 |a substituted phenylhydrazine 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Journal of Advanced Pharmaceutical Technology & Research, Vol 2, Iss 1, Pp 43-46 (2011) 
787 0 |n http://www.japtr.org/article.asp?issn=2231-4040;year=2011;volume=2;issue=1;spage=43;epage=46;aulast=Panneerselvam 
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787 0 |n https://doaj.org/toc/0976-2094 
856 4 1 |u https://doaj.org/article/4a986f51a9aa4be387bc75dbfc6e7dfb  |z Connect to this object online.