Effect of Plant Extracts on the Characteristics of Silver Nanoparticles for Topical Application

Silver nanoparticles (AgNPs) were synthesized using hydroalcoholic extracts of dittany (<i>Origanum dictamnus</i>), sage (<i>Salvia officinalis</i>), sea buckthorn (<i>Elaeagnus rhamnoides</i>, syn. <i>Hippophae rhamnoides</i>), and calendula (<i>...

Full description

Saved in:
Bibliographic Details
Main Authors: Ioanna K. Siakavella (Author), Fotini Lamari (Author), Dimitrios Papoulis (Author), Malvina Orkoula (Author), Patroula Gkolfi (Author), Michail Lykouras (Author), Konstantinos Avgoustakis (Author), Sophia Hatziantoniou (Author)
Format: Book
Published: MDPI AG, 2020-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_4abe51c27f3e4dbeaceed72c20b011b2
042 |a dc 
100 1 0 |a Ioanna K. Siakavella  |e author 
700 1 0 |a Fotini Lamari  |e author 
700 1 0 |a Dimitrios Papoulis  |e author 
700 1 0 |a Malvina Orkoula  |e author 
700 1 0 |a Patroula Gkolfi  |e author 
700 1 0 |a Michail Lykouras  |e author 
700 1 0 |a Konstantinos Avgoustakis  |e author 
700 1 0 |a Sophia Hatziantoniou  |e author 
245 0 0 |a Effect of Plant Extracts on the Characteristics of Silver Nanoparticles for Topical Application 
260 |b MDPI AG,   |c 2020-12-01T00:00:00Z. 
500 |a 10.3390/pharmaceutics12121244 
500 |a 1999-4923 
520 |a Silver nanoparticles (AgNPs) were synthesized using hydroalcoholic extracts of dittany (<i>Origanum dictamnus</i>), sage (<i>Salvia officinalis</i>), sea buckthorn (<i>Elaeagnus rhamnoides</i>, syn. <i>Hippophae rhamnoides</i>), and calendula (<i>Calendula officinalis</i>) as reducing agents. AgNPs synthesized using NaBH<sub>4</sub> and citric acid were used as control. The impact of the origin of the extract and preparation conditions (light, temperature, reaction time) on the properties of the synthesized AgNPs was investigated. The structure, morphology, composition, physicochemical characteristics, and colloidal stability were characterized using dynamic laser scattering (DLS), ultraviolet-visible spectrophotometry (UV-/Vis), XRD, X-ray fluorescence (XRF), TEM, and FTΙR. The reduction of total phenolic and flavonoid content of the extracts after the reaction of AgNPs synthesis was also determined. Low IC50 values for all types of AgNPs revealed good antioxidant activity, attributable to the phenolic and flavonoid content of their surface. The results suggest that plant extract selection is important to the green synthesis of AgNPs because it affects the kinetics of their synthesis as well as their morphology, physicochemical characteristics, and colloidal stability. In vitro permeation studies on porcine skin revealed that AgNPs remained at the upper layers of stratum corneum and did not penetrate the skin barrier after 4 h of cutaneous application suggesting the safety of their application on intact skin for a relatively short time. 
546 |a EN 
690 |a silver nanoparticles 
690 |a AgNP 
690 |a green chemistry 
690 |a plant extracts 
690 |a topical application 
690 |a skin permeation 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceutics, Vol 12, Iss 12, p 1244 (2020) 
787 0 |n https://www.mdpi.com/1999-4923/12/12/1244 
787 0 |n https://doaj.org/toc/1999-4923 
856 4 1 |u https://doaj.org/article/4abe51c27f3e4dbeaceed72c20b011b2  |z Connect to this object online.