Pediatric Hodgkin's lymphoma presenting with pseudo-achalasia and para-neoplastic neurological syndrome (Guillain-Barre): A case report

Introduction: Pseudo-achalasia (secondary achalasia): is a disorder produced by tumor at or near the gastro-esophageal junction, resulting in manifestation similar to those produced by achalasia. Dysphasia, regurgitation, and weight loss are the main presenting symptoms. Hodgkin's lymphoma is a...

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Main Author: Ramy Mohamed Ghazy (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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Summary:Introduction: Pseudo-achalasia (secondary achalasia): is a disorder produced by tumor at or near the gastro-esophageal junction, resulting in manifestation similar to those produced by achalasia. Dysphasia, regurgitation, and weight loss are the main presenting symptoms. Hodgkin's lymphoma is associated with multiple para-neoplastic neurological syndromes, of which demyelinating polyneuropathies are very unusual. Para-neoplastic neuropathies are difficult to diagnose, especially when they are the presenting features. Case presentation: We report a rare case of 11years old child who presented with pseudo-achalasia and Guillain-Barre syndrome, eventually diagnosed as Hodgkin's lymphoma. Conclusion: Hodgkin's lymphoma can present with pseudo-achalasia and may be associated with para-neoplastic neurological syndrome's.
Item Description:2468-1245
10.1016/j.phoj.2017.04.002