Development and validation of an RP-HPLC method for analysis of 2-(5-(4-chlorophenyl)-3-(ethoxycarbonyl)-2-methyl-1H-pyrrol-1-yl)propanoic acid and its impurities under different pH

• Main Authors: Vania Maslarska (Author), Stanislav Bozhanov (Author), Stanislava Vladimirova (Author), Lily Peikova (Author), Diana Tzankova (Author), Maya Georgieva (Author)
• Format: Book
• Published: Pensoft Publishers, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A simple, fast and selective stability indicating RP-HPLC method was applied for following the degradation and appearance of impurities of previously synthesized 2-(5-(4-chlorophenyl)-3-(ethoxycarbonyl)-2-methyl-1H-pyrrol-1-yl)propanoic acid. The chromatographic separation was achieved on a C18 colu...