The Impact of Opium Dependence and Cigarette Smoking on Human Semen Parameters

Introduction: To examine the effects of opium dependence and cigarette smoking on semen quality and sperm parameters, the semen quality of men who abuse opiates and/or smoke cigarettes was investigated in a retrospective study. Methods: Male partners of 1325 infertile couples attending the infertili...

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Main Authors: Seyed Noureddin Nematollahi-Mahani (Author), Fateme Labibi (Author), Zhinoosossadat Shahidzadeh yazdi (Author), Elahe Karamad (Author), Victoria Habibzadeh (Author), Tayebe Naderi (Author), Aliasghar Ketabchi (Author)
Format: Book
Published: Negah Institute for Scientific Communication, 2014-11-01T00:00:00Z.
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Summary:Introduction: To examine the effects of opium dependence and cigarette smoking on semen quality and sperm parameters, the semen quality of men who abuse opiates and/or smoke cigarettes was investigated in a retrospective study. Methods: Male partners of 1325 infertile couples attending the infertility clinic for intrauterine insemination (IUI) procedure were divided into non-smoking non-opium (NS/NO), smoking and non-opium (S/NO), non-smoking and opium (NS/O), smoking and opium (S/O), and opium dependence regardless of smoking status (O/RS) groups. Two samples were collected from each subject and were analyzed in accordance to WHO criteria. Results: Subjects in different groups were comparable regarding mean age, duration of abstinence, and familial history of infertility, whereas duration of infertility was longer in all groups than in NS/NO group (P<0.05). The volume of semen, liquefaction time and pH differed significantly between S/NO and NS/NO groups (P<0.05). In addition, more men in S/NO group were diagnosed to be teratozoospermic than other groups (P=0.018). Sperm progression was significantly lower in NS/O than in NS/NO group (P<0.05). Conclusion: These findings suggest that opium dependence and cigarette smoking alter semen and sperm production and quality differently.
Item Description:2322-3626
2322-3626