TRPA1 Antagonists for Pain Relief

• Main Authors: Ari Koivisto (Author), Niina Jalava (Author), Raymond Bratty (Author), Antti Pertovaara (Author)
• Format: Bog
• Udgivet: MDPI AG, 2018-11-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Here, we review the literature assessing the role of transient receptor potential ankyrin 1 (TRPA1), a calcium-permeable non-selective cation channel, in various types of pain conditions. In the nervous system, TRPA1 is expressed in a subpopulation of nociceptive primary sensory neurons, astroglia,...