TRPA1 Antagonists for Pain Relief

• Egile Nagusiak: Ari Koivisto (Egilea), Niina Jalava (Egilea), Raymond Bratty (Egilea), Antti Pertovaara (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2018-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Here, we review the literature assessing the role of transient receptor potential ankyrin 1 (TRPA1), a calcium-permeable non-selective cation channel, in various types of pain conditions. In the nervous system, TRPA1 is expressed in a subpopulation of nociceptive primary sensory neurons, astroglia,...