TRPA1 Antagonists for Pain Relief

• Autori principali: Ari Koivisto (Autore), Niina Jalava (Autore), Raymond Bratty (Autore), Antti Pertovaara (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2018-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Here, we review the literature assessing the role of transient receptor potential ankyrin 1 (TRPA1), a calcium-permeable non-selective cation channel, in various types of pain conditions. In the nervous system, TRPA1 is expressed in a subpopulation of nociceptive primary sensory neurons, astroglia,...