Mycetoma due to Nocardia Africana/Nova treated successfully with cotrimoxazole and moxifloxacin

Nocardia africana is a recently identified organism and has rarely been reported to cause mycetoma. Here we report the case of a 40-year-old woman who presented with discharging sinuses and nodules for the past 7 years along with few discrete axillary lymph nodes. Cultures and Maldi-TOF MS (Matrix-a...

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Main Authors: Molisha Bhandari (Author), Sushruta Kathuria (Author), Niti Khunger (Author), Bhawna Sharma (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Molisha Bhandari  |e author 
700 1 0 |a Sushruta Kathuria  |e author 
700 1 0 |a Niti Khunger  |e author 
700 1 0 |a Bhawna Sharma  |e author 
245 0 0 |a Mycetoma due to Nocardia Africana/Nova treated successfully with cotrimoxazole and moxifloxacin 
260 |b Wolters Kluwer Medknow Publications,   |c 2021-01-01T00:00:00Z. 
500 |a 2229-5178 
500 |a 10.4103/idoj.IDOJ_533_20 
520 |a Nocardia africana is a recently identified organism and has rarely been reported to cause mycetoma. Here we report the case of a 40-year-old woman who presented with discharging sinuses and nodules for the past 7 years along with few discrete axillary lymph nodes. Cultures and Maldi-TOF MS (Matrix-assisted laser desorption/ionization-time of flight mass spectrometry) method identified the causative organism as Nocardia africana/nova. The organism was acid-fast positive on modified Ziehl-Neelsen stain and Gram's stain revealed branched filamentous beaded gram-positive bacilli, while histopathology showed granulation tissue along with few ill-defined epithelioid cell granulomas, with giant cells. Based on the sensitivity report, the patient was started on tablet moxifloxacin and cotrimoxazole, and has shown considerable improvement at 2.5 months of follow-up. 
546 |a EN 
690 |a cutaneous nocardiosis 
690 |a mycetoma 
690 |a nocardia africana/nova 
690 |a treatment 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Indian Dermatology Online Journal, Vol 12, Iss 2, Pp 298-301 (2021) 
787 0 |n http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=2;spage=298;epage=301;aulast=Bhandari 
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856 4 1 |u https://doaj.org/article/4b34f3ba6c3a41aa93e8e4a6f156748a  |z Connect to this object online.