Pathophysiological role of omega pore current in channelopathies
In voltage-gated cation channels, a recurrent pattern for mutations is the neutralization of positively charged residues in the voltage-sensing S4 transmembrane segments. These mutations cause dominant ion channelopathies affecting many tissues such as brain, heart, and skeletal muscle. Recent studi...
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Main Authors: | Karin eJurkat-Rott (Author), James Richard Groome (Author), Frank eLehmann-Horn (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2012-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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