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Bone marrow stromal cells reduce low-dose cytarabine-induced differentiation of acute myeloid leukemia

Low-dose cytarabine (LDAC) is a standard therapy for elderly acute myeloid leukemia (AML) patients unfit for intensive chemotherapy. While high doses of cytarabine induce cytotoxicity, the precise mechanism of action of LDAC in AML remains elusive. In vitro studies have demonstrated LDAC-induced dif...

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Bibliographic Details
Main Authors: Tomislav Smoljo (Author), Barbara Tomic (Author), Hrvoje Lalic (Author), Vilma Dembitz (Author), Josip Batinic (Author), Antonio Bedalov (Author), Dora Visnjic (Author)
Format: Book
Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
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