Cover Image

Buccal acetaminophen provides fast analgesia: two randomized clinical trials in healthy volunteers

Gisèle Pickering,1–3 Nicolas Macian,1 Frédéric Libert,2,4 J Michel Cardot,1 Séverine Coissard,1 Philippe Perovitch,5 Marc Maury,5 Claude Dubray1–3 1CHU Clermont-Ferrand, Centre de Pharmacologie Clinique, Clermont-Ferrand, France; 2Inser...

Full description

Saved in:

Bibliographic Details
Main Authors:	Pickering G (Author), Macian N (Author), Libert F (Author), Cardot JM (Author), Coissard S (Author), Perovitch P (Author), Maury M (Author), Dubray C (Author)
Format:	Book
Published:	Dove Medical Press, 2014-09-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Paracetamol sharpens reflection and spatial memory: a double-blind randomized controlled study in healthy volunteers
by: Pickering G, et al.
Published: (2016)

The brain signature of paracetamol in healthy volunteers: a double-blind randomized trial
by: Pickering G, et al.
Published: (2015)

Comparative fasting bioavailability of two clopidogrel formulations in healthy Mediterranean volunteers: an in vitro–in vivo correlation
by: Zaid AN, et al.
Published: (2015)

"Protective Premedication": A comparative study of acetaminophen, gabapentin and combination of acetaminophen with gabapentin for post-operative analgesia
by: Kartik Syal, et al.
Published: (2010)

The investigation of the effects of Ramadan fasting on the mood state of healthy volunteer persons
by: Ozgur Erdem
Published: (2018)

Evaluating Novel Agarose-Based Buccal Gels Scaffold: Mucoadhesive and Pharmacokinetic Profiling in Healthy Volunteers
by: Muhammad Ali Syed, et al.
Published: (2022)

Pharmacokinetics and bioavailability study of two ondansetron oral soluble film formulations in fasting healthy male Chinese volunteers
by: Zhu YB, et al.
Published: (2015)

Bioequivalence study of two formulations of flupirtine maleate capsules in healthy male Chinese volunteers under fasting and fed conditions
by: Liu YF, et al.
Published: (2017)

Pharmacokinetics and Bioequivalence Evaluation of Two Montelukast Sodium Chewable Tablets in Healthy Chinese Volunteers Under Fasted and Fed Conditions
by: Li W, et al.
Published: (2021)

Exorbitant Drug Loading of Metformin and Sitagliptin in Mucoadhesive Buccal Tablet: In Vitro and In Vivo Characterization in Healthy Volunteers
by: Rouheena Shakir, et al.
Published: (2022)

Design of Mucoadhesive Strips for Buccal Fast Release of Tramadol
by: Nayla Francine Garcia Pastório, et al.
Published: (2021)

Bioequivalence of two quetiapine extended release tablets in Chinese healthy volunteers under fasting and fed conditions and effects of food on pharmacokinetic profiles
by: Huang X, et al.
Published: (2018)

Bioequivalence Study of Amitriptyline Hydrochloride Tablets in Healthy Chinese Volunteers Under Fasting and Fed Conditions
by: Zhai Y, et al.
Published: (2020)

Savor the flavor: A randomized double‐blind study assessing taste‐enhanced placebo analgesia in healthy volunteers
by: Matthias Zunhammer, et al.
Published: (2022)

A randomized single-dose, two-period crossover bioequivalence study of two fixed-dose Paracetamol/Orphenadrine combination preparations in healthy volunteers under fasted condition
by: Kit Yee Cheah, et al.
Published: (2020)

Bioequivalence of two oral formulations of nitazoxanide in healthy volunteers
by: Vinícius Marcondes REZENDE, et al.
Published: (2024)

Bioavailability of two oral formulas of secnidazole in healthy volunteers
by: Patrícia Andréa Bertuol Montovani, et al.
Published: (2009)

In vitro and in vivo characterization of domperidone-loaded fast dissolving buccal films
by: Gamal M. Zayed, et al.
Published: (2020)

Bioequivalence study of abacavir/lamivudine (600/300-mg) tablets in healthy Thai volunteers under fasting conditions
by: Ekawan Yoosakul, et al.
Published: (2016)

Evaluation of bioequivalence of two tablet forms of lisinopril in healthy volunteers
by: S. A. Altynbekov, et al.
Published: (2013)

Pharmacokinetics and Bioequivalence of Two Formulations of Azithromycin Tablets: A Randomized, Single-Dose, Three-Period, Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions
by: Yingrong Chen, et al.
Published: (2024)

Bioequivalence Study of Two Formulations of Tramadol Capsules in Healthy Myanmar Volunteers
by: Ye Htut Linn, et al.
Published: (2019)

Pharmacokinetics comparison of two pegylated interferon alfa formulations in healthy volunteers
by: Marisa Boff Costa, et al.
Published: (2018)

Bioequivalence of Two Formulations of Amoxicillin in Human Healthy Volunteers on (HPLC) Technique
by: Alaa K. Jabbar Alhamd
Published: (2017)

Bioequivalence of Two Formulations of Amoxicillin in Human Healthy Volunteers on (HPLC) Technique
by: Alaa K. Jabbar Alhamd
Published: (2017)

Milnacipran poorly modulates pain in patients suffering from fibromyalgia: a randomized double-blind controlled study
by: Pickering G, et al.
Published: (2018)

Bioequivalence and Safety of Bilastine 20 mg Orodispersible Tablets and Conventional Tablets: A Randomized, Single-Dose, Two-Period Crossover Study in Healthy Volunteers Under Fasting Conditions
by: Manuel Román, et al.
Published: (2024)

Opioid-sparing post-cesarean analgesia using intravenous diclofenac-acetaminophen combination: A prospective, randomized clinical trial
by: Nidhi Bhatia, et al.
Published: (2023)

Pharmacokinetics and tolerability of IDP-73152 mesylate after a single oral administration under fasted and fed conditions in healthy volunteers
by: Shin D, et al.
Published: (2019)

Overview and Future Potential of Fast Dissolving Buccal Films as Drug Delivery System for Vaccines
by: Mohammad Nasir Uddin, et al.
Published: (2019)

Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions
by: Wu Q, et al.
Published: (2020)

Pharmacokinetic comparison of sitagliptin and metformin HCl extended-release tablets versus JANUMET® XR in healthy volunteers under fasting and fed conditions
by: Linling Que, et al.
Published: (2023)

Evaluation of the bioequivalence of two formulations containing the combination of 400 mg of acetaminophen (paracetamol), 4 mg of phenylephrine and 4 mg of chlorpheniramine in capsules: open-label, three-way crossover study, partially replicated in healthy volunteers of both sexes
by: Alessandra Ferreira dos Santos, et al.
Published: (2020)

Fast-Dissolving Nifedipine and Atorvastatin Calcium Electrospun Nanofibers as a Potential Buccal Delivery System
by: Hassa A. Alshaya, et al.
Published: (2022)

Pharmacodynamic equivalence study of two preparations of eye drops, containing dorzolamide in healthy volunteers
by: Gatchev Emil M., et al.
Published: (2016)

Applications of β-limit Dextrin as a Matrix Forming Excipient for Fast Disintegrating Buccal Dosage Formats
by: Xin Qi, et al.
Published: (2013)

Pharmacokinetics of intranasal amiloride in healthy volunteers
by: Venkata K. Yellepeddi, et al.
Published: (2023)

The Effect Of Food On The Pharmacokinetic Properties And Bioequivalence Of Two Formulations Of Levocetirizine Dihydrochloride In Healthy Chinese Volunteers
by: Cheng Y, et al.
Published: (2019)

Bioequivalence study of dacomitinib and Vizimpro® in healthy Chinese volunteers under fasting and fed conditions: A randomized, open‐label, single‐dose, crossover trial
by: Xiaojia Yang, et al.
Published: (2023)

Oral versus intravenous acetaminophen as a constituent of multimodal analgesia after coronary artery bypass graft surgery: A randomized, blinded trial
by: Sajad Yarahmadi, et al.
Published: (2020)