First‐in‐human study of milvexian, an oral, direct, small molecule factor XIa inhibitor
Abstract Milvexian (BMS‐986177/JNJ‐70033093) is a small molecule, active‐site inhibitor of factor XIa (FXIa) being developed to prevent and treat thrombotic events. The safety, tolerability, pharmacokinetics (PKs), and pharmacodynamics (PDs) of milvexian were assessed in a two‐part, double‐blind, pl...
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Main Authors: | Vidya Perera (Author), Zhaoqing Wang (Author), Joseph Luettgen (Author), Danshi Li (Author), Mary DeSouza (Author), Michael Cerra (Author), Dietmar Seiffert (Author) |
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Format: | Book |
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Wiley,
2022-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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