Manasamitra Vatakam on Scopolamine-Induced Amnesia in Female Wistar Rats

BackgroundNeurodegenerative diseases induce amnesia, and effective treatment is still elusive. Aims and Objectives: The present study highlights the ameliorating effects of Manasa Mitra Vatakam (MMV) using behavioral parameters on scopolamine-induced memory loss in female Wistar rats. Materials and...

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Bibliographic Details
Main Authors: Sankar A (Author), Kandasamy Deepa (Author), Radhakrishan Anjuna (Author), Janaki C. S (Author), Sheriff Dhastangir (Author), Prabhu K (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2024-04-01T00:00:00Z.
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Summary:BackgroundNeurodegenerative diseases induce amnesia, and effective treatment is still elusive. Aims and Objectives: The present study highlights the ameliorating effects of Manasa Mitra Vatakam (MMV) using behavioral parameters on scopolamine-induced memory loss in female Wistar rats. Materials and MethodsMMV was compared with DPZ as a standard in the present study to determine the behavioral parameters through elevated plus maze (Hebb William maze/rectangular maze)and locomotor activity in scopolamine-induced memory loss in female Wistar rats. Results and DiscussionThe results of the study illustrate the effectiveness of MMV in reversing memory dysfunction and memory-enhancing effects. ConclusionThe study paves the way for exploring research in CNS disorders and its potential application in drug-induced neurotoxicity.
Item Description:0976-4879
0975-7406
10.4103/jpbs.jpbs_9_24