Calcipotriol/betamethasone dipropionate in the treatment of psoriasis vulgaris

Efstratios Vakirlis, Athanasios Kastanis, Demetrios IoannidesA’ Department of Dermatology, Aristotle University of Thessaloniki, GreeceAbstract: Psoriasis is one of the most common skin diseases. The mainstay of treatment for the vast majority of patients is topical therapy. A rising first...

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Main Authors: Efstratios Vakirlis (Author), Athanasios Kastanis (Author), Demetrios Ioannides (Author)
Format: Book
Published: Dove Medical Press, 2008-03-01T00:00:00Z.
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Summary:Efstratios Vakirlis, Athanasios Kastanis, Demetrios IoannidesA’ Department of Dermatology, Aristotle University of Thessaloniki, GreeceAbstract: Psoriasis is one of the most common skin diseases. The mainstay of treatment for the vast majority of patients is topical therapy. A rising first-line treatment modality for psoriasis vulgaris is the two-compound ointment containing calcipotriol 50 µg/g plus betamethasone dipropionate 0.5 mg/g (Dovobet®, Daivobet®, Taclonex®), which combines a vitamin D analog and a corticosteroid. This innovative formulation preserves the activity and bioavailability of the two components and many clinical studies have demonstrated that it has a greater efficacy, tolerability, and a rapid onset of action compared with its individual ingredients or tacalcitol.Keywords: psoriasis, calcipotriol/betamethasone dipropionate, dovobet, daivobet, taclonex
Item Description:1176-6336
1178-203X