Luteolin attenuates CCl4-induced hepatic injury by inhibiting ferroptosis via SLC7A11

• Main Authors: Zhiqiang Han (Author), Batudeligen (Author), Hongmei Chen (Author), Narisu (Author), Anda (Author), Yanhua Xu (Author), Lan Xue (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Luteolin (3,4,5,7-tetrahydroxy flavone) is reported to strongly protect from acute carbon tetrachloride (CCl4) -induced liver injury or fibrosis. Ferroptosis can be induced by hepatic injury, and contributes to liver fibrosis development. The exact functional mechanism underlying...