DNA polymerase ζ suppresses the radiosensitivity of glioma cells by regulating the PI3K/AKT/mTOR pathway

• Autori principali: Jiqiang Ding (Autore), Zhisheng Chen (Autore), Weilong Ding (Autore), Yongsheng Xiang (Autore), Junbao Yang (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Glioblastoma is the most common glioma with high mortality and poor prognosis. Radiation resistance is one of the large challenges in the treatment of glioma. The study aimed to identify whether DNA polymerase ζ affects glioma cell radiosensitivity. The mRNA and protein levels of REV3L and REV7 were...