FAIM Enhances the Efficacy of Mesenchymal Stem Cell Transplantation by Inhibiting JNK-Induced c-FLIP Ubiquitination and Degradation

• Main Authors: Jinyong Chen (Author), Feng Liu (Author), Wangxing Hu (Author), Yi Qian (Author), Dilin Xu (Author), Chenyang Gao (Author), Zhiru Zeng (Author), Si Cheng (Author), Lan Xie (Author), Kaixiang Yu (Author), Gangjie Zhu (Author), Xianbao Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The poor survival rates of transplanted mesenchymal stem cells (MSCs) in harsh microenvironments impair the efficacy of MSCs transplantation in myocardial infarction (MI). Extrinsic apoptosis pathways play an important role in the apoptosis of transplanted MSCs, and Fas apoptosis inhibit...