Prevalence and sociodemographic disparities of Hepatitis C in Baby Boomers and the US adult population
Background: The US Baby Boomer (BB) generation is associated with high rates of Hepatitis C virus (HCV) infection. There is limited literature detailing age-specific risk factors for HCV infection. Using a nationally representative sample, this study examines US adult HCV prevalence and age-specific...
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2019-01-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_4c78b4aae8564fa8a25f0089ea24feb5 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Kevin J. Moore |e author |
| 700 | 1 | 0 | |a Aliyah Gauri |e author |
| 700 | 1 | 0 | |a Tulay Koru-Sengul |e author |
| 245 | 0 | 0 | |a Prevalence and sociodemographic disparities of Hepatitis C in Baby Boomers and the US adult population |
| 260 | |b Elsevier, |c 2019-01-01T00:00:00Z. | ||
| 500 | |a 1876-0341 | ||
| 500 | |a 10.1016/j.jiph.2018.08.003 | ||
| 520 | |a Background: The US Baby Boomer (BB) generation is associated with high rates of Hepatitis C virus (HCV) infection. There is limited literature detailing age-specific risk factors for HCV infection. Using a nationally representative sample, this study examines US adult HCV prevalence and age-specific risk factors for chronic HCV infection. Methods: We analyzed data from National Health and Nutrition Examination Survey (NHANES) for years 1999-2012. Age was divided into three categories: BB, younger than BB (YG) and older than BB (OG). HCV status was determined by the presence of a positive HCV antibody and a positive HCV RNA. Sociodemographic variables were analyzed by HCV status. Multivariable logistic regression models adjusting for sociodemographic variables were fitted to identify age-specific risk factors for HCV positivity. Results: The overall prevalence of chronic HCV was 1.19% with a US population estimate of 2,347,852 US adults. BB had the highest prevalence at 2.23%, accounting for over 74% of all chronic HCV cases. HCV prevalence was highest among all ages (1.83%) and BB (2.71%) in 2001-2002 survey cycle. Among BB, males, non-Hispanic blacks, positive blood transfusion history, current and former smoker, and living below the poverty line were significant predictors of chronic HCV positivity. Conclusion: This study highlights the elevated prevalence of chronic HCV among BB and identifies age-specific risk factors for chronic HCV infection. As the BB population ages, it is important to use these generation-specific risk factors that can guide health professionals in targeted screening and public health prevention efforts. Keywords: Hepatitis C, Baby Boomers, Prevention, NHANES, Age-specific risk factors | ||
| 546 | |a EN | ||
| 690 | |a Infectious and parasitic diseases | ||
| 690 | |a RC109-216 | ||
| 690 | |a Public aspects of medicine | ||
| 690 | |a RA1-1270 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Journal of Infection and Public Health, Vol 12, Iss 1, Pp 32-36 (2019) | |
| 787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S1876034118301187 | |
| 787 | 0 | |n https://doaj.org/toc/1876-0341 | |
| 856 | 4 | 1 | |u https://doaj.org/article/4c78b4aae8564fa8a25f0089ea24feb5 |z Connect to this object online. |