The Inflammasome Signaling Pathway Is Actively Regulated and Related to Myocardial Damage in Coronary Thrombi from Patients with STEMI

• Main Authors: Jostein Nordeng (Author), Hossein Schandiz (Author), Svein Solheim (Author), Sissel Åkra (Author), Pavel Hoffman (Author), Borghild Roald (Author), Bjørn Bendz (Author), Harald Arnesen (Author), Ragnhild Helseth (Author), Ingebjørg Seljeflot (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The Nod-Like-Receptor-Protein-3 (NLRP3) inflammasome and the Interleukin-6 (IL-6) pathways are central mechanisms of the inflammatory response in myocardial reperfusion injury. Expanding our knowledge about the inflammasome signaling axis is important to improve treatment options. In a c...