Rubber Coring of Injectable Medication Vial Stoppers: An Evaluation of Causal Factors

Coring of a medication vial's rubber stopper has been reported as a major cause of visible particle presence in injectable preparations. In this study, we investigated and quantified visible particle formation caused by coring associated with four potential causal factors.

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Bibliographic Details
Main Authors: Chennell Philip (Author), Bourdeaux Daniel (Author), Citerne Quentin (Author), Arnaud Catherine (Author), Cosserant Sylvie (Author), Boiko-Alaux Véra (Author), Sautou Valerie (Author)
Format: Book
Published: De Gruyter, 2016-12-01T00:00:00Z.
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100 1 0 |a Chennell Philip  |e author 
700 1 0 |a Bourdeaux Daniel  |e author 
700 1 0 |a Citerne Quentin  |e author 
700 1 0 |a Arnaud Catherine  |e author 
700 1 0 |a Cosserant Sylvie  |e author 
700 1 0 |a Boiko-Alaux Véra  |e author 
700 1 0 |a Sautou Valerie  |e author 
245 0 0 |a Rubber Coring of Injectable Medication Vial Stoppers: An Evaluation of Causal Factors 
260 |b De Gruyter,   |c 2016-12-01T00:00:00Z. 
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500 |a 10.1515/pthp-2016-0015 
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546 |a EN 
690 |a rubber stoppers 
690 |a coring 
690 |a particulate matter 
690 |a needles 
690 |a intravenous administration 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Pharmaceutical industry 
690 |a HD9665-9675 
655 7 |a article  |2 local 
786 0 |n Pharmaceutical Technology in Hospital Pharmacy, Vol 1, Iss 4, Pp 165-174 (2016) 
787 0 |n https://doi.org/10.1515/pthp-2016-0015 
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787 0 |n https://doaj.org/toc/2365-242X 
856 4 1 |u https://doaj.org/article/4d1f2d6323a94d19b59b4413bd0ab1e1  |z Connect to this object online.