Differential Effect of Three Macrolide Antibiotics on Cardiac Pathology and Electrophysiology in a Myocardial Infarction Rat Model: Influence on Sodium Nav1.5 Channel Expression

• Main Authors: Noha E. Farag (Author), Mohamed K. El-Kherbetawy (Author), Hussein M. Ismail (Author), Ahmed M. Abdelrady (Author), Eman A. Toraih (Author), Walid Kamal Abdelbasset (Author), Rehab M. Lashine (Author), Mohammed EL-dosoky (Author), Sally Yussef Abed (Author), Khalid M. Ibraheem (Author), Manal S. Fawzy (Author), Sawsan A. Zaitone (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrolides were reported to have cardiotoxic effects presented mainly by electrocardiogram (ECG) changes with increased risk in cardiac patients. We aimed to determine the impact of three macrolides, azithromycin, clarithromycin and erythromycin, on cardiac electrophysiology, cardiac enzyme activiti...