In vivo analysis of the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic action in the chronic atrioventricular block cynomolgus monkeys
We analyzed the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic action using the chronic atrioventricular block cynomolgus monkeys with a cross-over design. Initially, moxifloxacin was intraven...
Saved in:
Main Authors: | Ai Goto (Author), Kengo Sakamoto (Author), Mihoko Hagiwara-Nagasawa (Author), Ryuichi Kambayashi (Author), Koki Chiba (Author), Yoshio Nunoi (Author), Hiroko Izumi-Nakaseko (Author), Yoshinori Takei (Author), Akio Matsumoto (Author), Atsushi Sugiyama (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2020-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes
by: Ai Goto, et al.
Published: (2020) -
Characterization of pathological remodeling in the chronic atrioventricular block cynomolgus monkey heart
by: Hiroko Izumi-Nakaseko, et al.
Published: (2023) -
Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventricular block dogs
by: Ai Goto, et al.
Published: (2019) -
Risperidone alone did not induce torsade de pointes: Experimental evidence from the chronic atrioventricular block model dogs
by: Yoshio Nunoi, et al.
Published: (2020) -
In vivo analysis of torsadogenic potential of an antipsychotic drug paliperidone using the acute atrioventricular block rabbit as a proarrhythmia model
by: Mihoko Hagiwara, et al.
Published: (2016)