HHV-8-Associated Multicentric Castleman Disease, a Diagnostic Challenge in a Patient With Acquired Immunodeficiency Syndrome and Fever
Patients with acquired immunodeficiency syndrome (AIDS) are at an increased susceptibility to pathogens and associated malignancies which can present with a unique constellation of symptoms. In this article, we describe a case of Castleman disease in a patient with AIDS, nonadherent with antiretrovi...
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SAGE Publishing,
2022-05-01T00:00:00Z.
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| 001 | doaj_4dd2dba18cfd4fbfaddb64cf3380cfc0 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Robert Dunn MS4 |e author |
| 700 | 1 | 0 | |a Roopam Jariwal MD |e author |
| 700 | 1 | 0 | |a Frederick Venter MD |e author |
| 700 | 1 | 0 | |a Shikha Mishra MD |e author |
| 700 | 1 | 0 | |a Janpreet Bhandohal MD |e author |
| 700 | 1 | 0 | |a Everado Cobos MD |e author |
| 700 | 1 | 0 | |a Arash Heidari MD |e author |
| 245 | 0 | 0 | |a HHV-8-Associated Multicentric Castleman Disease, a Diagnostic Challenge in a Patient With Acquired Immunodeficiency Syndrome and Fever |
| 260 | |b SAGE Publishing, |c 2022-05-01T00:00:00Z. | ||
| 500 | |a 2324-7096 | ||
| 500 | |a 10.1177/23247096221097526 | ||
| 520 | |a Patients with acquired immunodeficiency syndrome (AIDS) are at an increased susceptibility to pathogens and associated malignancies which can present with a unique constellation of symptoms. In this article, we describe a case of Castleman disease in a patient with AIDS, nonadherent with antiretroviral therapy (ART), who presented with fevers, constant abdominal pain, nausea, and vomiting. After an extensive work up, a lymph node biopsy confirmed a diagnosis of human herpesvirus-8 (HHV-8)-associated multicentric Castleman disease. Patients presenting with AIDS and fever have broad differential diagnoses; therefore, reaching a diagnosis as rare as Castleman disease can be challenging. HHV-8 has a propensity to CD20 positive B cells, which allows rituximab to be an effect treatment. | ||
| 546 | |a EN | ||
| 690 | |a Medicine (General) | ||
| 690 | |a R5-920 | ||
| 690 | |a Pathology | ||
| 690 | |a RB1-214 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Journal of Investigative Medicine High Impact Case Reports, Vol 10 (2022) | |
| 787 | 0 | |n https://doi.org/10.1177/23247096221097526 | |
| 787 | 0 | |n https://doaj.org/toc/2324-7096 | |
| 856 | 4 | 1 | |u https://doaj.org/article/4dd2dba18cfd4fbfaddb64cf3380cfc0 |z Connect to this object online. |