Preparation and in vivo evaluation of a highly skin- and nail-permeable efinaconazole topical formulation for enhanced treatment of onychomycosis

• Main Authors: Byung Chul Lee (Author), Rudra Pangeni (Author), Jungtae Na (Author), Kyo-Tan Koo (Author), Jin Woo Park (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Onychomycosis is a progressive fungal infection of the nails that involves the deeper nail layer and nail bed. It is important to maintain sufficient drug concentration in the diseased tissues after topical application. In this study, a stable topical delivery system for efinaconazole (EFN) was desi...