In vitro and in vivo metabolism of psilocybin's active metabolite psilocin
In vivo, psilocybin is rapidly dephosphorylated to psilocin which induces psychedelic effects by interacting with the 5-HT2A receptor. Psilocin primarily undergoes glucuronidation or conversion to 4-hydroxyindole-3-acetic acid (4-HIAA). Herein, we investigated psilocybin's metabolic pathways in...
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Main Authors: | Jan Thomann (Author), Karolina E. Kolaczynska (Author), Oliver V. Stoeckmann (Author), Deborah Rudin (Author), Patrick Vizeli (Author), Marius C. Hoener (Author), Christopher R. Pryce (Author), Franz X. Vollenweider (Author), Matthias E. Liechti (Author), Urs Duthaler (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2024-04-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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