A quick algorithmic review on management of viral infectious diseases in pediatric solid organ transplant recipients

Pediatric solid organ transplant is a life-saving procedure for children with end-stage organ failure. Viral infections are a common complication following pediatric solid organ transplantation (SOT), which can lead to increased morbidity and mortality. Pediatric solid organ transplant recipients ar...

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Main Authors: Marjan Moghadamnia (Author), Hamid Eshaghi (Author), Hosein Alimadadi (Author), Simin Dashti-Khavidaki (Author)
Format: Book
Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
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100 1 0 |a Marjan Moghadamnia  |e author 
700 1 0 |a Hamid Eshaghi  |e author 
700 1 0 |a Hosein Alimadadi  |e author 
700 1 0 |a Simin Dashti-Khavidaki  |e author 
245 0 0 |a A quick algorithmic review on management of viral infectious diseases in pediatric solid organ transplant recipients 
260 |b Frontiers Media S.A.,   |c 2023-09-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2023.1252495 
520 |a Pediatric solid organ transplant is a life-saving procedure for children with end-stage organ failure. Viral infections are a common complication following pediatric solid organ transplantation (SOT), which can lead to increased morbidity and mortality. Pediatric solid organ transplant recipients are at an increased risk of viral infections due to their immunosuppressed state. The most commonly encountered viruses include cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV), varicella-zoster virus (VZV), adenoviruses, and BK polyomavirus. Prevention strategies include vaccination prior to transplantation, post-transplant prophylaxis with antiviral agents, and preemptive therapy. Treatment options vary depending on the virus and may include antiviral therapy and sometimes immunosuppression modification. This review provides a Quick Algorithmic overview of prevention and treatment strategies for viral infectious diseases in pediatric solid organ transplant recipient. 
546 |a EN 
690 |a pediatrics 
690 |a solid organ 
690 |a transplantation 
690 |a viral infections 
690 |a antiviral 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 11 (2023) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fped.2023.1252495/full 
787 0 |n https://doaj.org/toc/2296-2360 
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