Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages
It has been suggested that the supernatant of LPSstimulated macrophages (macrophage nociceptive factor, MNF) promotes nociception in mice. Intraperitoneal administration of MNF induced dose-related writhing, which reached a plateau between 18 and 26 min after injection and decreased within 60 min. T...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
1997-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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