Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway

• Main Authors: Lili Wang (Author), Rufeng Ma (Author), Yubo Guo (Author), Jing Sun (Author), Haixia Liu (Author), Ruyuan Zhu (Author), Chenyue Liu (Author), Jun Li (Author), Lin Li (Author), Beibei Chen (Author), Liping Sun (Author), Jinfa Tang (Author), Dandan Zhao (Author), Fangfang Mo (Author), Jianzhao Niu (Author), Guangjian Jiang (Author), Min Fu (Author), Dieter Brömme (Author), Dongwei Zhang (Author), Sihua Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: This study is designed to explore whether Fructus ligustri lucidi (FLL) exhibits antioxidant effect in ovariectomized (OVX) rats, and to identify the signaling pathway involved in this process.Methods: OVX rats were treated with FLL aqueous extract (3.5 g/kg) for 12 weeks. Serum, uteri, and...