N-Acetyl Cysteine Overdose Inducing Hepatic Steatosis and Systemic Inflammation in Both Propacetamol-Induced Hepatotoxic and Normal Mice

• Main Authors: Gunn-Guang Liou (Author), Cheng-Chi Hsieh (Author), Yi-Ju Lee (Author), Pin-Hung Li (Author), Ming-Shiun Tsai (Author), Chi-Ting Li (Author), Sue-Hong Wang (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acetaminophen (APAP) overdose induces acute liver damage and even death. The standard therapeutic dose of N-acetyl cysteine (NAC) cannot be applied to every patient, especially those with high-dose APAP poisoning. There is insufficient evidence to prove that increasing NAC dose can treat patients wh...