IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway
Abstract Aims and background IFI16 plays an important role in innate immunity against invasive microbial infection by sensing double-stranded DNA viruses due to caspase-1-dependent inflammasome activation and subsequent maturation and secretion of IL-1β. However, the role of IFI16 in regulating the...
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Main Authors: | Li Liu (Author), Shuangshuang Xie (Author), Cheng Li (Author), Yue Guo (Author), Xiaoyan Liu (Author), Xiuhua Zhao (Author), Qiang Li (Author), Wenjun Du (Author) |
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Format: | Book |
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BMC,
2022-04-01T00:00:00Z.
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