New Role of Adult Lung c-kit+ Cells in a Mouse Model of Airway Hyperresponsiveness

• Main Authors: Giuseppe Spaziano (Author), Donato Cappetta (Author), Konrad Urbanek (Author), Elena Piegari (Author), Grazia Esposito (Author), Maria Matteis (Author), Manuela Sgambato (Author), Gioia Tartaglione (Author), Rosa Russo (Author), Raffaele De Palma (Author), Francesco Rossi (Author), Antonella De Angelis (Author), Bruno D'Agostino (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Structural changes contribute to airway hyperresponsiveness and airflow obstruction in asthma. Emerging evidence points to the involvement of c-kit+ cells in lung homeostasis, although their potential role in asthma is unknown. Our aim was to isolate c-kit+ cells from normal mouse lungs and to test...