Potential role of Lu/BCAM in HIV-related atherosclerosis
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules....
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| Main Authors: | , , |
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| Format: | Book |
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AOSIS,
2019-09-01T00:00:00Z.
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| Summary: | Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients. |
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| Item Description: | 2225-2002 2225-2010 10.4102/ajlm.v8i1.792 |