Squalene Loaded Nanoparticles Effectively Protect Hepatic AML12 Cell Lines against Oxidative and Endoplasmic Reticulum Stress in a TXNDC5-Dependent Way

• Main Authors: Seyed Hesamoddin Bidooki (Author), Teresa Alejo (Author), Javier Sánchez-Marco (Author), Roberto Martínez-Beamonte (Author), Roubi Abuobeid (Author), Juan Carlos Burillo (Author), Roberto Lasheras (Author), Victor Sebastian (Author), María J. Rodríguez-Yoldi (Author), Manuel Arruebo (Author), Jesús Osada (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Virgin olive oil, the main source of fat in the Mediterranean diet, contains a substantial amount of squalene which possesses natural antioxidant properties. Due to its highly hydrophobic nature, its bioavailability is reduced. In order to increase its delivery and potentiate its actions, squalene h...