Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus

• Main Authors: Jon Egaña-Huguet (Author), Miquel Saumell-Esnaola (Author), Svein Achicallende (Author), Edgar Soria-Gomez (Author), Itziar Bonilla-Del Río (Author), Gontzal García del Caño (Author), Sergio Barrondo (Author), Joan Sallés (Author), Inmaculada Gerrikagoitia (Author), Nagore Puente (Author), Izaskun Elezgarai (Author), Pedro Grandes (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule cell (GC) dendritic spines mediates a type of long-term depression (LTD) of the excitatory medial perforant path (MPP) synapses independent o...