Renal and liver injury following the treatment of COVID-19 by remdesivir

Remdesivir initially was intravenously administrated to treat the Ebola disease however right now it has been administered to treat COVID-19 in some countries. However it is necessary to find the exact effect of remdesivir in patients with COVID-19. Remdesivir solution is administered with a cyclode...

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Bibliographic Details
Main Authors: Mohsen Mohammad Rahimi (Author), Elham Jahantabi (Author), Behzad Lotfi (Author), Mehdi Forouzesh (Author), Rohollah Valizadeh (Author), Saman Farshid (Author)
Format: Book
Published: Society of Diabetic Nephropathy Prevention, 2021-04-01T00:00:00Z.
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Summary:Remdesivir initially was intravenously administrated to treat the Ebola disease however right now it has been administered to treat COVID-19 in some countries. However it is necessary to find the exact effect of remdesivir in patients with COVID-19. Remdesivir solution is administered with a cyclodextrin carrier that filters solely by the glomeruli; thereby patients with abnormal renal function cannot eliminate it quickly; therefore, remdesivir can lead to renal failure or liver dysfunction during therapeutic process of COVID-19. Assessment of renal function in patients with COVID-19 who have acute kidney injury (AKI) or end-stage renal disease is fundamental.
Item Description:2251-8363
2251-8819
10.34172/jnp.2021.10