GENETICS OF PSORIASIS AND PSORIATIC ARTHRITIS

Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the...

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Main Authors: V. Ibba (Author), M. Piga (Author), G. Porru (Author), G. Passiu (Author), A. Mameli (Author), A. Vacca (Author), A. Cauli (Author), A. Mathieu (Author), V. Mura (Author), S. Anna (Author)
Format: Book
Published: PAGEPress Publications, 2011-09-01T00:00:00Z.
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Summary:Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed. Key words: Genetics, psosriasis, psoriatic arthritis
Item Description:10.4081/reumatismo.2007.1s.25
0048-7449
2240-2683