Effect of Garlic and Alcoholic Extract on the Mitrogenic Soralene Antifungal in Mushrooms Aspergillus amstelodami

• Main Authors: Rafea Al-Taee (Author), Rafeah Jarjees (Author)
• Format: Book
• Published: College of Education for Pure Sciences, 2007-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

This study includes testing the effect of four subinhibitory concentrations of garlic extracts (aqueous and alcoholic) on the mutagenicity of 8-methoxypsoralen (8-MOP) in the presence of long wave ultraviolet (UV A) in conidia of the fungus Aspergillus amstelodami .The concentrations of aqueous extract were used in this study are (2.5 , 5 , 7.5 and 10 mg I ml media ) and the concentrations of alcoholic extracts are ( 0.5 , 1 , 1.5 and 2 mg I ml media) . Two protocols were used to study the effect of garlic extracts on the mutagenicity of 8- MOP in the presence of UV A (366 nm) . In first protocol , the pretreatment method , all the concentrations (2.5 , 5 , 7.5 and 10 mg I ml )<br />of aqueous extract increased the mutants frequencies which were induced with 8-MOP + UV A, but only the low concentration (0.5 mg I ml) of the alcoholic extract increases the frequency of the mutants induced with 8-<br />MOP + UV A . In the second protocol , the growth mediated method , both the aqueous and alcoholic extracts showed inhibitory effect on the mutagenicity of 8-MOP + UV A.

Item Description

1812-125X
2664-2530
10.33899/edusj.2007.162831