Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate

• المؤلفون الرئيسيون: Randa Mohammed Zaki (مؤلف), Munerah M. Alfadhel (مؤلف), Manal A. Alossaimi (مؤلف), Lara Ayman Elsawaf (مؤلف), Vidya Devanathadesikan Seshadri (مؤلف), Alanood S. Almurshedi (مؤلف), Rehab Mohammad Yusif (مؤلف), Mayada Said (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using Design-Expert^® software....