Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate

• Hauptverfasser: Randa Mohammed Zaki (Verfasst von), Munerah M. Alfadhel (Verfasst von), Manal A. Alossaimi (Verfasst von), Lara Ayman Elsawaf (Verfasst von), Vidya Devanathadesikan Seshadri (Verfasst von), Alanood S. Almurshedi (Verfasst von), Rehab Mohammad Yusif (Verfasst von), Mayada Said (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-07-01T00:00:00Z.
• Schlagworte: article
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This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using Design-Expert^® software....