Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate

• Κύριοι συγγραφείς: Randa Mohammed Zaki (Συγγραφέας), Munerah M. Alfadhel (Συγγραφέας), Manal A. Alossaimi (Συγγραφέας), Lara Ayman Elsawaf (Συγγραφέας), Vidya Devanathadesikan Seshadri (Συγγραφέας), Alanood S. Almurshedi (Συγγραφέας), Rehab Mohammad Yusif (Συγγραφέας), Mayada Said (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2022-07-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using Design-Expert^® software....