Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate

• Үндсэн зохиолчид: Randa Mohammed Zaki (Зохиогч), Munerah M. Alfadhel (Зохиогч), Manal A. Alossaimi (Зохиогч), Lara Ayman Elsawaf (Зохиогч), Vidya Devanathadesikan Seshadri (Зохиогч), Alanood S. Almurshedi (Зохиогч), Rehab Mohammad Yusif (Зохиогч), Mayada Said (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using Design-Expert^® software....