Central Composite Optimization of Glycerosomes for the Enhanced Oral Bioavailability and Brain Delivery of Quetiapine Fumarate

• Автори: Randa Mohammed Zaki (Автор), Munerah M. Alfadhel (Автор), Manal A. Alossaimi (Автор), Lara Ayman Elsawaf (Автор), Vidya Devanathadesikan Seshadri (Автор), Alanood S. Almurshedi (Автор), Rehab Mohammad Yusif (Автор), Mayada Said (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

This study aimed to formulate and statistically optimize glycerosomal formulations of Quetiapine fumarate (QTF) to increase its oral bioavailability and enhance its brain delivery. The study was designed using a Central composite rotatable design using Design-Expert^® software....