In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

• المؤلفون الرئيسيون: Giosuè Costa (مؤلف), Annalisa Maruca (مؤلف), Roberta Rocca (مؤلف), Francesca Alessandra Ambrosio (مؤلف), Emanuela Berrino (مؤلف), Fabrizio Carta (مؤلف), Francesco Mesiti (مؤلف), Alessandro Salatino (مؤلف), Delia Lanzillotta (مؤلف), Francesco Trapasso (مؤلف), Anna Artese (مؤلف), Stefano Alcaro (مؤلف), Claudiu T. Supuran (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2020-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The tumor-associated isoenzymes <i>h</i>CA IX and <i>h</i>CA XII catalyze the hydration of carbon dioxide to bicarbonate and protons. These isoforms are highly overexpressed in many types of cancer, where they contribute to the acidification of the tumor environment, promotin...